BDBM111024 US8614253, 3-55::US8614253, 3-63::US9241942, 3-63::US9963434, Compound 3-63

SMILES COc1cccc(C=O)c1O

InChI Key InChIKey=JJVNINGBHGBWJH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 111024   

LigandPNGBDBM111024(US8614253, 3-63 | US8614253, 3-55 | US9241942, 3-6...)
Affinity DataIC50: 2.37E+3nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
Go to US Patent

LigandPNGBDBM111024(US8614253, 3-63 | US8614253, 3-55 | US9241942, 3-6...)
Affinity DataIC50: 5.75E+3nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
Go to US Patent

LigandPNGBDBM111024(US8614253, 3-63 | US8614253, 3-55 | US9241942, 3-6...)
Affinity DataIC50: 2.37E+3nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM111024(US8614253, 3-63 | US8614253, 3-55 | US9241942, 3-6...)
Affinity DataIC50: 5.75E+3nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM111024(US8614253, 3-63 | US8614253, 3-55 | US9241942, 3-6...)
Affinity DataIC50: 2.37E+3nMAssay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

LigandPNGBDBM111024(US8614253, 3-63 | US8614253, 3-55 | US9241942, 3-6...)
Affinity DataIC50: 5.75E+3nMAssay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetToll-like receptor 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM111024(US8614253, 3-63 | US8614253, 3-55 | US9241942, 3-6...)
Affinity DataIC50: 2.42E+4nMAssay Description:Antagonist activity at TLR1/TLR2 in HEK-Blue hTLR2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetToll-like receptor 6(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM111024(US8614253, 3-63 | US8614253, 3-55 | US9241942, 3-6...)
Affinity DataIC50: 3.72E+4nMAssay Description:Antagonist activity at TLR2/TLR6 in human THP-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed