BDBM111013 US8614253, 3-44::US9241942, 3-44::US9963434, Compound 3-44

SMILES Oc1ccc(Br)cc1C=O

InChI Key InChIKey=MKKSTJKBKNCMRV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 111013   

LigandPNGBDBM111013(US8614253, 3-44 | US9241942, 3-44 | US9963434, Com...)
Affinity DataIC50: 1.33E+3nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
Go to US Patent

LigandPNGBDBM111013(US8614253, 3-44 | US9241942, 3-44 | US9963434, Com...)
Affinity DataIC50: 1.33E+3nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM111013(US8614253, 3-44 | US9241942, 3-44 | US9963434, Com...)
Affinity DataIC50: 1.33E+3nMAssay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

LigandPNGBDBM111013(US8614253, 3-44 | US9241942, 3-44 | US9963434, Com...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of rat intestinal alpha-glucosidase using p-nitrophenyl- alpha-D-glucopyranoside as substrate preincubated for 5 min before addition of su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article