BDBM110974 US8614253, 3-5::US9241942, 3-5::US9963434, Compound 3-5

SMILES COc1ccc(Br)c(C=O)c1O

InChI Key InChIKey=JUPJZUTYDWXZAQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 110974   

LigandPNGBDBM110974(US8614253, 3-5 | US9241942, 3-5 | US9963434, Compo...)
Affinity DataIC50: 80nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM110974(US8614253, 3-5 | US9241942, 3-5 | US9963434, Compo...)
Affinity DataIC50: 80nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM110974(US8614253, 3-5 | US9241942, 3-5 | US9963434, Compo...)
Affinity DataIC50: 80nMAssay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM110974(US8614253, 3-5 | US9241942, 3-5 | US9963434, Compo...)
Affinity DataIC50: 80nMAssay Description:Inhibition of IRE1 (unknown origin) assessed as reduction in XBP1 splicingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed