BDBM110570 US8614234, 38::US9725433, 38

SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(c3)-c3cc(c[nH]3)C(=O)NCCCN3CCOCC3)cc2)c1

InChI Key InChIKey=URFHWIMCQUTTHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110570   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM110570(US8614234, 38 | US9725433, 38)
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM110570(US8614234, 38 | US9725433, 38)
Affinity DataIC50: 10nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent