BDBM110073 US8609678, 4-(bis(2-fluorophenyl)(hydroxy)methyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [126]

SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)C(O)(c1ccccc1F)c1ccccc1F

InChI Key InChIKey=FLVXKXXWRURAER-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110073   

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110073(US8609678, 4-(bis(2-fluorophenyl)(hydroxy)methyl)-...)
Affinity DataIC50: 3nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110073(US8609678, 4-(bis(2-fluorophenyl)(hydroxy)methyl)-...)
Affinity DataIC50: 74nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent