BDBM109897 US20240150367, Compound 41::US8609647, 41

SMILES CC1(C)CCN(C(=O)CC#N)C11CCN(C1)c1ncnc2[nH]ccc12

InChI Key InChIKey=IRKRUMKFBUIGLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 109897   

TargetTyrosine-protein kinase JAK3(Human)
Japan Tobacco

US Patent
LigandPNGBDBM109897(US8609647, 41 | US20240150367, Compound 41)
Affinity DataIC50: 90nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Japan Tobacco

US Patent
LigandPNGBDBM109897(US8609647, 41 | US20240150367, Compound 41)
Affinity DataIC50: 90nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent