BDBM109890 US20240150367, Compound 34::US8609647, 34

SMILES CC1N(CCC11CCCN1C(=O)CC#N)c1ncnc2[nH]ccc12

InChI Key InChIKey=IYDLRLWVPRJBCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 109890   

TargetTyrosine-protein kinase JAK3(Human)
Japan Tobacco

US Patent
LigandPNGBDBM109890(US8609647, 34 | US20240150367, Compound 34)
Affinity DataIC50: 36nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Japan Tobacco

US Patent
LigandPNGBDBM109890(US8609647, 34 | US20240150367, Compound 34)
Affinity DataIC50: 36nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent