BDBM109767 US10667515, Compound (S)-anabasine::US8609708, 59 Anabasine

SMILES C1CC[C@H](NC1)c1cccnc1

InChI Key InChIKey=MTXSIJUGVMTTMU-UHFFFAOYSA-N

Data  2 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 109767   

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM109767(US8609708, 59 Anabasine | US10667515, Compound (S)...)
Affinity DataIC50: 3.24E+4nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetResistance to inhibitors of cholinesterase protein 3(Pig roundworm)
Iowa State University Research Foundation

US Patent
LigandPNGBDBM109767(US8609708, 59 Anabasine | US10667515, Compound (S)...)
Affinity DataEC50:  1.26E+3nMAssay Description:Nematode eggs are isolated from fresh feces by centrifugation and flotation. The eggs are washed and inspected to confirm embryonation has not starte...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM109767(US8609708, 59 Anabasine | US10667515, Compound (S)...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat brain alpha4beta2 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM109767(US8609708, 59 Anabasine | US10667515, Compound (S)...)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at rat brain alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM109767(US8609708, 59 Anabasine | US10667515, Compound (S)...)
Affinity DataKi:  390nMAssay Description:Displacement of 125I-alpha-bungarotoxin from rat brain alpha7 nAChR by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM109767(US8609708, 59 Anabasine | US10667515, Compound (S)...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of 3H-cytisine from rat brain alpha4beta2 nAChR by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed