BDBM10959 (3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-(2-methylphenyl)carbamate::2-methylphenserine::tolserine::tolserine.tartaric acid

SMILES [H][C@]12N(C)CC[C@@]1(C)c1cc(OC(=O)Nc3ccccc3C)ccc1N2C

InChI Key InChIKey=JGAGHIIOCADQOV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 10959   

TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 1.95E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 1.95E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human erythrocyte AChE using acetyl-(beta-methyl)thiocholine as substrate by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human plasma BChE using S-butyrylthiocholine as substrate by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed