BDBM10930 3-{[methyl({3-[(4-oxo-2-phenyl-4H-chromen-7-yl)oxy]propyl})amino]methyl}phenyl N-butylcarbamate hydrochloride::CHEMBL128043::aminoalkoxyheteroaryl deriv. 23

SMILES CCCCNC(=O)Oc1cccc(CN(C)CCCOc2ccc3c(c2)oc(cc3=O)-c2ccccc2)c1

InChI Key InChIKey=ZRALBZBQZUJSPR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10930   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10930(CHEMBL128043 | 3-{[methyl({3-[(4-oxo-2-phenyl-4H-c...)
Affinity DataIC50: 31nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10930(CHEMBL128043 | 3-{[methyl({3-[(4-oxo-2-phenyl-4H-c...)
Affinity DataIC50: 31nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM10930(CHEMBL128043 | 3-{[methyl({3-[(4-oxo-2-phenyl-4H-c...)
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM10930(CHEMBL128043 | 3-{[methyl({3-[(4-oxo-2-phenyl-4H-c...)
Affinity DataIC50: 800nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide preincubated for 20 mins before [14C]-anandamide addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed