BDBM109232 6-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetrahydronaphthalen-2-yl)picolinic acid (Compound 3)::CHEMBL2398173
SMILES OC(=O)c1cccc(n1)-c1ccc2CCCC(=NNc3nc4ccccc4s3)c2c1
InChI Key InChIKey=ZGERKAMDOWOUTN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 109232
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Walter and Eliza Hall Institute of Medical Research
Walter and Eliza Hall Institute of Medical Research
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Walter and Eliza Hall Institute of Medical Research
Walter and Eliza Hall Institute of Medical Research
Affinity DataIC50: 6.80E+4nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Walter and Eliza Hall Institute of Medical Research
Walter and Eliza Hall Institute of Medical Research
Affinity DataIC50: 20nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Walter and Eliza Hall Institute of Medical Research
Walter and Eliza Hall Institute of Medical Research
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKd: 4.10nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl assessed as dissociation rate by surface plasmon resonance assayMore data for this Ligand-Target Pair