BDBM108454 US8604016, 11::US9938267, Cmpd ID 11

SMILES O=C(Cc1ccccc1)Nc1nnc(CCCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1

InChI Key InChIKey=IAGMXTIWZLWUOZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 108454   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108454(US8604016, 11 | US9938267, Cmpd ID 11)
Affinity DataIC50: 1.40E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108454(US8604016, 11 | US9938267, Cmpd ID 11)
Affinity DataIC50: 1.40E+3nMAssay Description:No preinc (Column 4).More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108454(US8604016, 11 | US9938267, Cmpd ID 11)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed