BDBM107517 US8598357, 20

SMILES O=C(CC#N)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1

InChI Key InChIKey=ZJUQDFIINDCGDS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 107517   

TargetD(3) dopamine receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM107517(US8598357, 20)
Affinity DataKi:  3.12nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM107517(US8598357, 20)
Affinity DataKi:  22.4nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM107517(US8598357, 20)
Affinity DataKi:  203nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
Go to US Patent