BDBM10695 3-{[methyl(3-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-2,3-dihydro-1-benzofuran-6-yl]oxy}propyl)amino]methyl}phenyl methylcarbamate::3-{[methyl(3-{[(2Z)-2-(naphthalen-1-ylmethylidene)-3-oxo-2,3-dihydro-1-benzofuran-6-yl]oxy}propyl)amino]methyl}phenyl N-methylcarbamate::Xanthostigmine deriv. 9b

SMILES CNC(=O)Oc1cccc(CN(C)CCCOc2ccc3C(=O)C(Oc3c2)=Cc2cccc3ccccc23)c1

InChI Key InChIKey=JAEZFUCFEMHOTF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10695   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10695(3-{[methyl(3-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-...)
Affinity DataIC50: 6.86nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10695(3-{[methyl(3-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-...)
Affinity DataIC50: 44.3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10695(3-{[methyl(3-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-...)
Affinity DataIC50: 6.86nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed