BDBM105190 4-amino-3-bromopyridine::EN300-81773

SMILES Nc1ccncc1Br

InChI Key InChIKey=DDQYSZWFFXOXER-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 105190   

TargetPolymerase acidic protein [1-204,T86I,G186S](2009 H1N1 Influenza)
Rutgers University

LigandPNGBDBM105190(4-amino-3-bromopyridine | EN300-81773)
Affinity DataIC50: 1.00E+6nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM105190(4-amino-3-bromopyridine | EN300-81773)
Affinity DataIC50: 2.18E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM105190(4-amino-3-bromopyridine | EN300-81773)
Affinity DataIC50: 2.10E+6nMAssay Description:Inhibition of HIV-1 reverse transcriptase RT52A mutant using ABTS as substrate preincubated with compound for 1 hr followed by template-primer additi...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)