BDBM104817 US8569299, 3

SMILES Cc1nc(C2CCN(CC2)C(=O)[C@@H]2CC(C[C@H]2c2ccc(F)cc2F)N2CCC(F)(F)C2)n(n1)-c1ccc(Cl)c(C)c1

InChI Key InChIKey=YDDWJIZGOLMUPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104817   

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM104817(US8569299, 3)
Affinity DataIC50: 9.80nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent