BDBM10425 2-(8-{[(1S,12S,14R)-14-hydroxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-6(17),7,9,15-tetraen-9-yl]oxy}octyl)-2,3-dihydro-1H-isoindole-1,3-dione::6-O-Demethyl-6-O-(8 -phthalimidooctyl)-galanthamine::galanthamine deriv. 7d

SMILES CN1CC[C@@]23C=C[C@H](O)C[C@@H]2Oc2c3c(C1)ccc2OCCCCCCCCN1C(=O)c2ccccc2C1=O

InChI Key InChIKey=HCUFJSXAWLKFHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10425   

TargetAcetylcholinesterase(Pacific electric ray)
Cnrs

LigandPNGBDBM10425(6-O-Demethyl-6-O-(8 -phthalimidooctyl)-galanthamin...)
Affinity DataIC50: 2.50E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
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Date in BDB:
7/31/2006
Entry Details Article
PubMed