BDBM10402 7-methyl-12-{[(2R)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}-4-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),7,10,12-pentaene-3,5-dione::pyrrolo[3,4-c]quinoline 8e

SMILES Cc1nn(C)c(C)c1N1C(=O)c2c(C1=O)c1cc(ccc1nc2C)S(=O)(=O)N1CCC[C@@H]1COc1ccccc1

InChI Key InChIKey=RRSFJALKJAFQPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10402   

TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandPNGBDBM10402(7-methyl-12-{[(2R)-2-(phenoxymethyl)pyrrolidine-1-...)
Affinity DataIC50: 55nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed