BDBM10392 7-methyl-4-(2-methylphenyl)-12-(morpholine-4-sulfonyl)-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1(13),2(6),7,9,11-pentaene-3,5-dione::pyrrolo[3,4-c]quinoline 6r

SMILES Cc1nc2ccc(cc2c2C(=O)N(C(=O)c12)c1ccccc1C)S(=O)(=O)N1CCOCC1

InChI Key InChIKey=SFKADFFMDQELSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10392   

TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandPNGBDBM10392(7-methyl-4-(2-methylphenyl)-12-(morpholine-4-sulfo...)
Affinity DataIC50: 15nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed