BDBM103905 JNK3 inhibitor 2::US8563583, C-1

SMILES COc1cc(ccc1OCCO)-n1ccc(cc1=O)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=JCLKKRZMUZBICB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103905   

TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

LigandPNGBDBM103905(JNK3 inhibitor 2 | US8563583, C-1)
Affinity DataIC50: 136nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM103905(JNK3 inhibitor 2 | US8563583, C-1)
Affinity DataKi:  3nMpH: 7.4Assay Description:Compounds were characterized in an in vitro binding assay to determine their Ki or ability to antagonized binding of a peptide agonist to the human m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent