BDBM103903 Disubstituted aryl-Me ATX inhibitor 10::US8563583, A-29

SMILES COc1ccc(\C=C2/SC(=NC2=O)N2CCN(C)CC2)cc1OC

InChI Key InChIKey=UFGZHNAAQZTLQP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103903   

LigandPNGBDBM103903(Disubstituted aryl-Me ATX inhibitor 10 | US8563583...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activities of hit compounds towards ENPP1-5 were calculated using pNP-TMP, and the inhibitory activities of hit compounds towards ENPP6 an...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM103903(Disubstituted aryl-Me ATX inhibitor 10 | US8563583...)
Affinity DataKi:  29nMpH: 7.4Assay Description:Compounds were characterized in an in vitro binding assay to determine their Ki or ability to antagonized binding of a peptide agonist to the human m...More data for this Ligand-Target Pair
In DepthDetails
US Patent