BDBM10375 7-methyl-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1(13),2(6),7,9,11-pentaene-3,5-dione::cid_611339::pyrrolo[3,4-c]quinoline 6a

SMILES Cc1nc2ccccc2c2C(=O)NC(=O)c12

InChI Key InChIKey=RDOYVWRCQYHNHO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10375   

TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandPNGBDBM10375(7-methyl-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetProtein LANA1(HHV-8)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM10375(7-methyl-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1...)
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay