BDBM103590 US10201527, Compound 84::US10736881, Compound 84::US8551988, 84

SMILES CN(C)CC(C)(C)Cn1c(CCc2ccc(F)cc2)nc2cc(\C=C\C(=O)NO)ccc12

InChI Key InChIKey=GBOHZZWBYZOFFN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103590   

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM103590(US8551988, 84 | US10201527, Compound 84 | US107368...)
Affinity DataIC50: 54nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM103590(US8551988, 84 | US10201527, Compound 84 | US107368...)
Affinity DataIC50: 54nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM103590(US8551988, 84 | US10201527, Compound 84 | US107368...)
Affinity DataIC50: 54nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent