BDBM10333 4-[(2,3-dioxo-5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indol-1-yl)methyl]phenyl acetate::Acetic Acid (S)-4-[2,3-Dioxo-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-2,3-dihydroindol-1-yl-methyl]phenyl Ester::Pyrrolidine Isatin Analogue 11e

SMILES CC(=O)Oc1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N2CCC[C@H]2COc2ccccc2)cc1

InChI Key InChIKey=BSDZXTVQJICEPK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 10333   

TargetCaspase-3(Human)
Washington University

LigandPNGBDBM10333(Acetic Acid (S)-4-[2,3-Dioxo-5-(2-phenoxymethyl-py...)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM10333(Acetic Acid (S)-4-[2,3-Dioxo-5-(2-phenoxymethyl-py...)
Affinity DataIC50: 34.8nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-1(Human)
Washington University

LigandPNGBDBM10333(Acetic Acid (S)-4-[2,3-Dioxo-5-(2-phenoxymethyl-py...)
Affinity DataIC50: 5.00E+4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM10333(Acetic Acid (S)-4-[2,3-Dioxo-5-(2-phenoxymethyl-py...)
Affinity DataIC50: 5.00E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM10333(Acetic Acid (S)-4-[2,3-Dioxo-5-(2-phenoxymethyl-py...)
Affinity DataIC50: 5.00E+4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM10333(Acetic Acid (S)-4-[2,3-Dioxo-5-(2-phenoxymethyl-py...)
Affinity DataIC50: 12.0nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed