BDBM10311 5-(azepan-1-ylsulfonyl)-1H-indole-2,3-dione::5-(azepane-1-sulfonyl)-2,3-dihydro-1H-indole-2,3-dione::Isatin Sulfonamide 22

SMILES O=C1Nc2ccc(cc2C1=O)S(=O)(=O)N1CCCCCC1

InChI Key InChIKey=MLWAHVYFMDBXBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10311   

TargetCaspase-3(Human)
Glaxosmithkline

LigandPNGBDBM10311(5-(azepane-1-sulfonyl)-2,3-dihydro-1H-indole-2,3-d...)
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Glaxosmithkline

LigandPNGBDBM10311(5-(azepane-1-sulfonyl)-2,3-dihydro-1H-indole-2,3-d...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed