BDBM10306 (R)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isatin::5-{[(2R)-2-(methoxymethyl)pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indole-2,3-dione::Isatin Sulfonamide 17

SMILES COC[C@H]1CCCN1S(=O)(=O)c1ccc2NC(=O)C(=O)c2c1

InChI Key InChIKey=SLQMNVJNDYLJSF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10306   

TargetCaspase-3(Human)
Glaxosmithkline

LigandPNGBDBM10306(5-{[(2R)-2-(methoxymethyl)pyrrolidine-1-]sulfonyl}...)
Affinity DataIC50: 1.80E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed