BDBM10206 (3S)-3-(6-{[3-(4-methyl-5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)benzene]sulfonamido}-2-phenylhexanamido)-4-oxobutanoic acid::sulfonamide analog 28

SMILES Cn1c(noc1=O)-c1cccc(c1)S(=O)(=O)NCCCCC(C(=O)N[C@@H](CC(O)=O)C=O)c1ccccc1

InChI Key InChIKey=OIHKIMZFXOWDMN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10206   

TargetCaspase-3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM10206((3S)-3-(6-{[3-(4-methyl-5-oxo-4,5-dihydro-1,2,4-ox...)
Affinity DataKi:  1.80E+3nM ΔG°:  -7.83kcal/moleT: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed