BDBM10205 (3S)-4-oxo-3-(6-{[3-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)benzene]sulfonamido}-2-phenylhexanamido)butanoic acid::sulfonamide analog 27

SMILES OC(=O)C[C@H](NC(=O)C(CCCCNS(=O)(=O)c1cccc(c1)-c1nc(=O)o[nH]1)c1ccccc1)C=O

InChI Key InChIKey=LFZNRJIBQMYAOO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10205   

TargetCaspase-3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM10205((3S)-4-oxo-3-(6-{[3-(5-oxo-4,5-dihydro-1,2,4-oxadi...)
Affinity DataKi:  100nM ΔG°:  -9.54kcal/moleT: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed