BDBM101449 US8524710, 27

SMILES FC(F)(F)c1ccccc1S(=O)(=O)[C@H]1C[C@H](N(C1)c1ccnc(n1)C#N)C(=O)N1CCC1

InChI Key InChIKey=WWUYFNOCKPGASZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101449   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM101449(US8524710, 27)
Affinity DataIC50: 1.65nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2013
Entry Details
Go to US Patent