BDBM101245 US8524722, 151

SMILES CC(C)N(C)C\C=C\C(=O)N1CCc2c(C1)sc1ncc(C#N)c(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c21

InChI Key InChIKey=LGPPNTOFGJQREB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101245   

TargetEpidermal growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM101245(US8524722, 151)
Affinity DataIC50: 6.40nMpH: 7.0 T: 2°CAssay Description:EGFR inhibitory activity of compounds of the present invention is quantified employing the EGFR HTRF assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
Go to US Patent