BDBM101227 US8524722, 10

SMILES Fc1ccc(Nc2ncnc3sc4CN(CCc4c23)C(=O)\C=C\CN2C3CCC2CC3)cc1Cl

InChI Key InChIKey=ZXPWQTWHRXRMRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101227   

TargetEpidermal growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM101227(US8524722, 10)
Affinity DataIC50: 1.10nMpH: 7.0 T: 2°CAssay Description:EGFR inhibitory activity of compounds of the present invention is quantified employing the EGFR HTRF assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
Go to US Patent