BDBM10104 (3Z)-5-fluoro-4-[(3R)-4-hydroxy-3-[(2-hydroxyethyl)amino]but-1-yn-1-yl]-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one::4-alkynyl oxindole 7j

SMILES COc1cc[nH]c1\C=C1/C(=O)Nc2ccc(F)c(C#C[C@H](CO)NCCO)c12

InChI Key InChIKey=LICPCHXULHJNTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10104   

LigandPNGBDBM10104((3Z)-5-fluoro-4-[(3R)-4-hydroxy-3-[(2-hydroxyethyl...)
Affinity DataIC50: 95nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2006
Entry Details Article
PubMed