BDBM101027 US8507479, 665

SMILES CCCCc1ccc(nc1)C(=O)Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)SCC1(F)F

InChI Key InChIKey=HZVDYOJJNKICNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101027   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM101027(US8507479, 665)
Affinity DataIC50: 870nMAssay Description:Beta-Secretase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM101027(US8507479, 665)
Affinity DataIC50: 870nMpH: 7.0Assay Description:Inhibition assay using human BACE-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
Go to US Patent