BDBM10085 (3Z)-4-[3-(hydroxymethyl)piperidin-1-yl]-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-5-nitro-2,3-dihydro-1H-indol-2-one::(Z)-4-(3-Hydroxymethyl-piperidinyl)-3-(3-methoxy-1H-pyrrol-2-ylmethylene) -5- nitro -1,3-dihydro-indol-2-one::C-4 substituted oxindole inhibitor 7i

SMILES COc1cc[nH]c1\C=C1/C(=O)Nc2ccc(c(N3CCCC(CO)C3)c12)N(=O)=O

InChI Key InChIKey=MQLFYKBUKMKFOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10085   

LigandPNGBDBM10085((Z)-4-(3-Hydroxymethyl-piperidinyl)-3-(3-methoxy-1...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed