BDBM100747 CHEMBL2397007::US8507714, 151

SMILES CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1cncc(c1)C(O)=O

InChI Key InChIKey=KDRKKWDEBBFSDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100747   

TargetChymase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM100747(CHEMBL2397007 | US8507714, 151)
Affinity DataIC50: 380nMAssay Description:Inhibitory activity of the compounds for recombinant human chymase was measured by method of Pasztor et al. (Pasztor et al., Acta Biol. Hung. 42:285-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2013
Entry Details
Go to US Patent

TargetChymase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM100747(CHEMBL2397007 | US8507714, 151)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed