BDBM100746 CHEMBL246560::US8507714, 150::US8507714, 277

SMILES CC[C@@H](NC(=O)N1CC(=O)NC[C@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(O)=O)c(N)c1

InChI Key InChIKey=ZQCPJAZKZATEMD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 100746   

TargetChymase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM100746(US8507714, 277 | US8507714, 150 | CHEMBL246560)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity of the compounds for recombinant human chymase was measured by method of Pasztor et al. (Pasztor et al., Acta Biol. Hung. 42:285-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2013
Entry Details
Go to US Patent

TargetChymase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM100746(US8507714, 277 | US8507714, 150 | CHEMBL246560)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity of the compounds for recombinant human chymase was measured by method of Pasztor et al. (Pasztor et al., Acta Biol. Hung. 42:285-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2013
Entry Details
Go to US Patent

TargetChymase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM100746(US8507714, 277 | US8507714, 150 | CHEMBL246560)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM100746(US8507714, 277 | US8507714, 150 | CHEMBL246560)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed