BDBM1000 4-hydroxy-3-[(2-phenoxyethyl)sulfanyl]-2H-chromen-2-one::Hydroxycoumarin deriv. 38::I-Hydroxy-3-[ (2-phenoxyethy1)thio]-2H-1-benzopyran-2-one

SMILES Oc1c(SCCOc2ccccc2)c(=O)oc2ccccc12

InChI Key InChIKey=PFVQVVKQDJSYFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1000   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM1000(4-hydroxy-3-[(2-phenoxyethyl)sulfanyl]-2H-chromen-...)
Affinity DataIC50: 2.40E+4nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2004
Entry Details Article
PubMed