BDBM50607315 BAY-069

SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl

InChI Key InChIKey=UNSHMXUHOHBLIQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50607315   

LigandPNGBDBM50607315(BAY-069)
Affinity DataIC50: 186nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50607315(BAY-069)
Affinity DataIC50: 186nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50607315(BAY-069)
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50607315(BAY-069)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50607315(BAY-069)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50607315(BAY-069)
Affinity DataIC50: 153nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, cytoplasmic(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607315(BAY-069)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAspartate aminotransferase, mitochondrial(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607315(BAY-069)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GOT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed