BDBM50565800 Azd-1390::Azd1390::US20240294545, Compound AZD1390
SMILES CC(C)n1c2c(cnc3cc(F)c(cc23)-c2ccc(OCCCN3CCCCC3)nc2)n(C)c1=O
InChI Key InChIKey=VQSZIPCGAGVRRP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50565800
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of ATM (unknown origin) assessed as ATM-dependent phosphorylation using GST-p53 ser15 as substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 6.55E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Competitive inhibition of ATM (unknown origin) measured by ATP-competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:(1) Preparation of 1× kinase basal buffer and reaction termination solution1) 1× kinase basal buffer50 mM HEPES, pH 7.50.0015% Brij-35 (polyoxyethyle...More data for this Ligand-Target Pair