BDBM50260153 Apamin::CHEMBL525408::Octadecapeptide venom
SMILES CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N2)NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)[C@@H](C)O
InChI Key InChIKey=YVIIHEKJCKCXOB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50260153
TargetSmall conductance calcium-activated potassium channel protein 3(Human)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 0.168nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 3(Human)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 3(Human)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 0.168nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 3(Human)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0240nMAssay Description:Inhibition of rat SK Calcium channelMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rat)
University of Li£Ge
Curated by ChEMBL
University of Li£Ge
Curated by ChEMBL
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rat)
University of Li£Ge
Curated by ChEMBL
University of Li£Ge
Curated by ChEMBL
Affinity DataKi: 0.00400nMAssay Description:Displacement of [125I]apamin from Wistar rat cortical apamin-sensitive siteMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rat)
University of Li£Ge
Curated by ChEMBL
University of Li£Ge
Curated by ChEMBL
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair