BDBM64452 2-(diethylamino)ethyl 4-aminobenzoate hydrochloride::2-(diethylamino)ethyl 4-azanylbenzoate hydrochloride::4-aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride::Anuject::Geriocaine::Gerokit::Hewedolor-Procain::MLS001304095::Procaine::SAMPL3, G2::SMR000718771::cid_5795

SMILES CCN(CC)CCOC(=O)c1ccc(N)cc1

InChI Key InChIKey=MFDFERRIHVXMIY-UHFFFAOYSA-N

Data  2 IC50  1 EC50  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 64452   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64452(2-(diethylamino)ethyl 4-azanylbenzoate hydrochlori...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
LigandPNGBDBM64452(2-(diethylamino)ethyl 4-azanylbenzoate hydrochlori...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM64452(2-(diethylamino)ethyl 4-azanylbenzoate hydrochlori...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 64452   

HostPNGBDBM197280(SAMPL3, H1)
University of California San Diego

GuestPNGBDBM64452(2-(diethylamino)ethyl 4-azanylbenzoate hydrochlori...)
ITC DataΔG°: -7.09kcal/mole logk: 1.50E+5
pH: 7.4 T: 24.85°C