BDBM50285551 3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid::Agaric acid::CHEMBL78764

SMILES CCCCCCCCCCCCCCCCC(C(O)=O)C(O)(CC(O)=O)C(O)=O

InChI Key InChIKey=HZLCGUXUOFWCCN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50285551   

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes of Health

LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50: 2.35E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChaperonin GroEL(Escherichia coli)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of ATPase activity of Escherichia coli GroEL expressed in Escherichia coliDH5alpha incubated for 60 mins using ATP by spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThiosulfate sulfurtransferase(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of native rhodanese (unknown origin) assessed as reduction in rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target60 kDa heat shock protein, mitochondrial(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes of Health

LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50: 2.35E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed