BDBM50124208 ASP-015K::ASP015K::Peficitinib
SMILES NC(=O)c1cnc2[nH]ccc2c1N[C@H]1[C@H]2CC3C[C@@H]1C[C@](O)(C3)C2
InChI Key InChIKey=DREIJXJRTLTGJC-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50124208
Affinity DataIC50: 4.80nMAssay Description:Inhibition of Tyk2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human JAK1 using Biotin-Lyn-Substrate-2 as substrate assessed as reduction in rate of substrate phosphorylation incubated for 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human JAK2 using Biotin-Lyn-Substrate-2 as substrate assessed as reduction in rate of substrate phosphorylation incubated for 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human JAK3 using Biotin-Lyn-Substrate-2 as substrate assessed as reduction in rate of substrate phosphorylation incubated for 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human TYK2 using Biotin-IRS1-Substrate as substrate assessed as reduction in rate of substrate phosphorylation incubated for 1 hr in pr...More data for this Ligand-Target Pair