BDBM50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53
SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31
InChI Key InChIKey=VMWNQDUVQKEIOC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 252 hits for monomerid = 50001955
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
Affinity DataEC50: 3.29E+3nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
TargetM18 aspartyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 3.67E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
TargetProcathepsin L(Human)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.96E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Affinity of the Compound for Dopamine receptor D2 in rat striatal membrane was determined in vitro using Dopamine Antagonist [3H]-spiperone as ligand...More data for this Ligand-Target Pair
Affinity DataIC50: 302nMAssay Description:Neuroleptic activity in terms of [3H]spiroperidol binding in rat striatal membrane to Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 432nMAssay Description:In vitro binding affinity towards rat Dopamine receptor D1 by [3H]SCH-23390 displacement.More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:In vitro binding affinity towards rat Dopamine receptor D2 by [3H]spiperone displacement.More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Affinity for [3H]N-propylnorapomorphine (NPA) Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Concentration inhibiting specific binding of [3H]haloperidol to Dopamine receptor D2 from rat striatal brain.More data for this Ligand-Target Pair
Affinity DataIC50: 444nMAssay Description:Binding affinity against Dopamine receptor D1 from rat brain corpus striatum membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Binding affinity against Dopamine receptor D2 from rat brain corpus striatum membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Evaluated for the affinity against Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKd: 127nMAssay Description:Compound was evaluated for the ability to displace [3H]spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as low affinity stateMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Alpha-2 adrenergic receptor activity assessed in vitro for displacement of [3H]clonidine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKd: 0.660nMAssay Description:Compound was evaluated for the ability to displace [3H]spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as low affinity stateMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKd: 600nMAssay Description:In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
Affinity DataEC50: 4.30nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 5.80nMAssay Description:Agonist activity at human D2 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at ferret D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at ferret D4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of binding of [3H]spiroperidol to Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHOK1 cells assessed as calcium mobilization by radiometric and luminescence plate counti...More data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at rat D2 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Agonist activity at rat D4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human recombinant dopamine D2 receptor expressed in rat pituitary cells assessed as inhibition of forskolin-stimulated cAMP accum...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at human recombinant dopamine D3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 384nMAssay Description:In vitro binding affinity to Dopamine receptor D1 in rat striatal membranes using D1 antagonist [3H]SCH-23390More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:In vitro binding affinity to Dopamine receptor D2 in rat striatal membranes using D2 antagonist [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at rat D2 dopamine receptor expressed in CHOK1 cells assessed as [35S]GTPgammaS binding after 90 mins by liquid scintillation counte...More data for this Ligand-Target Pair
Affinity DataIC50: 384nMAssay Description:Affinity of the Compound for Dopamine D1 receptor in rat striatal membrane was determined in vitro using Dopamine Antagonist [3H]SCH-23390 as ligand.More data for this Ligand-Target Pair
Affinity DataIC50: 238nMAssay Description:In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 384nMAssay Description:Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of [3H]N-propylnorapomorphine as radioligand for Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 384nMAssay Description:Compound was tested in vitro for binding affinity towards Dopamine receptor D1 in rat striatal membrane by using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Compound was tested in vitro for binding affinity towards Dopamine receptor D2 in rat striatal membrane by using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Compound was evaluated for the inhibition of [3H]spiperone binding to dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was evaluated for the inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1 of rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKd: 680nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D2A expressed in COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.More data for this Ligand-Target Pair