BDBM50011132 ALLINI-1::CHEMBL3259891

SMILES COC(C(O)=O)c1c(C)nc2ccc(Br)cc2c1-c1ccc(Cl)cc1

InChI Key InChIKey=BNDPDYQQAJUJPY-UHFFFAOYSA-N

Data  6 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50011132   

TargetGag-Pol polyprotein(HIV-1)
The Ohio State University

LigandPNGBDBM50011132(CHEMBL3259891 | ALLINI-1)
Affinity DataIC50: 910nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein [A1275T](HIV-1)
The Ohio State University

LigandPNGBDBM50011132(CHEMBL3259891 | ALLINI-1)
Affinity DataIC50: 2.62E+5nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
The Ohio State University

LigandPNGBDBM50011132(CHEMBL3259891 | ALLINI-1)
Affinity DataIC50: 400nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein [A1275T](HIV-1)
The Ohio State University

LigandPNGBDBM50011132(CHEMBL3259891 | ALLINI-1)
Affinity DataIC50: 4.61E+3nMAssay Description:A recently reported time-resolved fluorescence assay [J. Biol. Chem. 287: 21189-21203] was used to quantify IN 3'-processing and strand transfer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011132(CHEMBL3259891 | ALLINI-1)
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50011132(CHEMBL3259891 | ALLINI-1)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)