BDBM11392 (4R)-4-amino-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide::AL-8520

SMILES COCCCN1C[C@H](N)c2cc(sc2S1(=O)=O)S(N)(=O)=O

InChI Key InChIKey=MVBJPOIMDXIBKC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11392   

TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11392((4R)-4-amino-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4...)
Affinity DataIC50: 1.28nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11392((4R)-4-amino-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4...)
Affinity DataIC50: 1.30nMAssay Description:Concentration which produces 50% inhibition of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM11392((4R)-4-amino-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4...)
Affinity DataIC50: 128nMAssay Description:Concentration which produces 50% Inhibition of human Carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed