BDBM50292340 AKUAMMICINE::CHEMBL508955

SMILES COC(=O)C1[C@H]2C[C@@H]3N(CC[C@]33C1=Nc1ccccc31)C\C2=C\C

InChI Key InChIKey=UMGIOBCVRLYQOW-UHFFFAOYSA-N

Data  7 KI  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50292340   

TargetAcetylcholinesterase(Electric eel)
TBA

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 2.21E+5nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article

TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 8.24E+3nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 7.94E+3nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 240nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 251nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 1.24E+4nMAssay Description:Agonist activity at mouse FLAG-tagged delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 1.26E+4nMAssay Description:Agonist activity at mouse FLAG-tagged delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataEC50:  3.98E+4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in U2OS cells assessed as beta-arrestin2 recruitment incubated for 90 mins by PathHunter as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  3.31E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D5 receptor (unknown origin) expressed in HEK-293T cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  2.32E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  2.51E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed