BDBM50160807 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,6,7,8,9,10-hexahydro-cycloocta[b]pyridine::AD-5423::Blonanserin::CHEMBL178803

SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1

InChI Key InChIKey=XVGOZDAJGBALKS-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50160807   

TargetD(2) dopamine receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  0.140nMAssay Description:In vitro binding affinity against recombinant human dopamine receptor D2L in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  0.810nMAssay Description:In vitro binding affinity against recombinant human 5-hydroxytryptamine 2A receptor in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  3.98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  14.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  56.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  286nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  2.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetD(1A) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  2.87E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  2.99E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetHistamine H1 receptor(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  3.01E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi:  7.68E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Dainippon Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50160807(AD-5423 | 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazi...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed