BDBM31892 9-cis retinoic acid::9C-RA::CHEMBL705::Panretin::alitretinoin
SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
InChI Key InChIKey=SHGAZHPCJJPHSC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 149 hits for monomerid = 31892
Affinity DataKd: 0.800nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 0.300nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
Affinity DataKd: 9nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor alpha using transactivation a...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Compound was tested for binding affinity against retinoic acid receptor using 5 nM of [3H]RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Compound was tested for binding affinity against retinoid X receptor using 5 nM of [3H]9-cis-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of [3H]9-cis-RA binding to mouse Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 74nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 219nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Binding affinity against retinoic Acid gamma receptors co-transfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Binding affinity against retinoic Acid alpha receptors co-transfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Binding affinity against retinoic Acid beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Binding affinity against retinoic Acid X alpha receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Binding affinity against retinoic Acid X gamma receptors co-transfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Binding affinity against retinoic Acid X beta receptors co-transfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.30nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Transcriptional activation of Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 102nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Relative activity against Retinoic acid receptor RAR alpha compared to ATRAMore data for this Ligand-Target Pair
Affinity DataEC50: 4.30nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Effective concentration against RXR-alpha receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Binding affinity against retinoic Acid gamma receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Binding affinity against retinoic Acid X gamma receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Binding affinity against retinoic Acid X alpha receptors co-transfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Binding affinity against retinoic Acid alpha receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Binding affinity against retinoic Acid beta receptors co-transfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 52nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 304nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 316nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Dissociation constant for binding to Retinoid X receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Transcriptional activation of Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Transcriptional activation of Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Transcriptional activation of Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Dissociation constant for binding to Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Dissociation constant for binding to Retinoid X receptor gammaMore data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Dissociation constant for binding to Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataKd: 32nMAssay Description:Dissociation constant for binding to Retinoid X receptor alphaMore data for this Ligand-Target Pair