BDBM50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755
SMILES CCCN(CCC)C1CCc2ccc(O)cc2C1
InChI Key InChIKey=BLYMJBIZMIGWFK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 64 hits for monomerid = 50020222
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
Affinity DataKd: 0.670nMAssay Description:Tested for binding affinity against dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataEC50: 39.8nMAssay Description:Agonist activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.531nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse ATt-20 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Potency to displace the specific in vitro binding of [3H]DP-5,6-ADTN to rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 0.950nMAssay Description:Agonist activity at dopamine D3 receptor in human U2OS-D3 cells assessed as EA-tagged beta-arrestin translocation after 1.5 hrs by luminescence based...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]prazosin binding (0.4 nM) to rat isolated brain membr...More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:50% inhibition of specific [3H]clonidine binding (0.4 nM) to Alpha-2 adrenergic receptors in rat isolated brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Agonist activity at Rattus norvegicus (rat) dopamine D2 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-s...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D2 trunk/D2 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 192nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D2 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Tested for inhibition of the binding of [125I]NCQ298 to dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Tested in vitro for the inhibition of [3H]U-86170 binding to Dopamine receptor D3, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 2.35nMAssay Description:Displacement of [3H]spiperone from cloned dopamine D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.35nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Tested in vitro for the inhibition of [3H]raclopride binding to Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Tested for the inhibitory activity against Dopamine D3 receptor in infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Tested for inhibition of the binding of [125I]NCQ298 to dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibitory activity against [125I]- NCQ298 binding to dopamine receptor D3 in Sf 9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.19nMAssay Description:Displacement of [3H]Spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.19nMAssay Description:Displacement of [3H]spiperone from rat D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.19nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 23.2nMAssay Description:Tested for the inhibitory activity against sigma receptor rat cerebellarMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Tested in vitro for the inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of the radioligand [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 72.7nMAssay Description:Tested for the inhibitory activity against 5-hydroxytryptamine 1A receptor in rat hippocampalMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [125I]trans-8-OH-PIPAT in membrane homogenates of hippocampal tissue ...More data for this Ligand-Target Pair
Affinity DataKi: 142nMAssay Description:Tested for the inhibitory activity against D2H (high-affinity states) receptor in infected HEK 293 cells.More data for this Ligand-Target Pair
Affinity DataKi: 142nMAssay Description:Tested for inhibition of the binding of [125I]NCQ298 to D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 142nMAssay Description:Inhibitory activity against [125I]- NCQ298 binding to dopamine receptor D2 in Sf 9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 143nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair